The FDA applies strict bioequivalence standards to narrow therapeutic index (NTI) drugs like warfarin and phenytoin, requiring tighter limits (90-111%) and replicate studies to ensure patient safety. These rules prevent dangerous fluctuations in blood levels that can occur with standard generics.
View MoreIVIG therapy uses antibodies from healthy donors to calm overactive immune systems in autoimmune disorders. It works fast, is safe for many patients, and helps with conditions like CIDP, ITP, and Guillain-Barré syndrome - but it's costly and requires frequent infusions.
View MoreLearn how to prevent dangerous dosing errors with liquid medications by using the right tools-oral syringes over cups and spoons. Follow FDA and USP guidelines for accurate milliliter-based dosing.
View MoreLearn how to safely assess the risks of using expired medications when no alternatives exist. Understand which drugs are dangerous past their date, how storage affects potency, and when it's better to go without.
View MoreLearn how to manage high medication costs during Medicare Part D's coverage gap (donut hole) before it disappears in 2025. Discover proven strategies to save hundreds or thousands on prescriptions.
View MoreCoenzyme Q10 may help reduce muscle pain caused by statins, but evidence is mixed. Learn what studies show, the right dose to try, and how it compares to other options for statin side effects.
View MoreHydroxyzine can cause dangerous QT prolongation and life-threatening heart rhythms, especially in older adults or those on other medications. Learn who's at risk, what to watch for, and safer alternatives.
View MoreMixing antihistamines and alcohol can multiply drowsiness by up to 300%, increasing risks of accidents, falls, and impaired driving. First-generation drugs like Benadryl are especially dangerous, but even 'non-drowsy' options like Zyrtec and Claritin carry risks when combined with alcohol.
View MoreCaffeine can interfere with common medications like warfarin, levothyroxine, and antidepressants, leading to reduced effectiveness or dangerous side effects. Learn which drugs are risky and how to stay safe.
View MoreParoxetine can cause significant weight gain over time, especially after six months of use. Learn why it happens, how it compares to other antidepressants, and what you can do to manage or reverse it.
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